Recombinant GSDMD Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81473-50, E-AB-81473-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: GSDMD
Target Synonym: DF5L; DFNA5L; FKSG10; GSDMDC1; GSDMD
Research Areas: Cell Biology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: WB
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R06-5C5
UNIProt ID: P57764
Background: GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.
Concentration: 300 μg/mL
Immunogen: Recombinant protein of human GSDMD
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:1000
Calculated MW: 53kDa
Observed MW: 53kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only