Recombinant Integrin beta 5 Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81574-50, E-AB-81574-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: Integrin beta 5
Target Synonym: FLJ26658; Integrin beta-5; Integrin subunit beta 5; integrin; beta 5; ITB5; Itgb5; Testis secretory sperm-binding protein Li 217p
Research Areas: Cancer, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat, Hamster
Application: WB
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R04-0G6
UNIProt ID: P18084
Background: Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors.
Concentration: 300 μg/mL
Immunogen: Recombinant protein of human Integrin beta 5
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:500-1:1000
Calculated MW: 88kDa
Observed MW: 88kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only