Recombinant Lactate Dehydrogenase A Monoclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: E-AB-81451-50, E-AB-81451-100
Citations, Manuals and MSDS Available upon request.
Abbreviation: Lactate Dehydrogenase A
Target Synonym: Cell proliferation-inducing gene 19 protein; GSD11; L lactate dehydrogenase A chain; l7R2; LDH M; LDH muscle subunit; LDH1; PIG19 Proliferation-inducing gene 19
Research Areas: Cancer, Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: WB
Isotype: IgG
Clonality: Rabbit Monoclonal
Clone No.: R09-9A7
UNIProt ID: P00338
Background: LDHA, also named as LDH-M and NY-REN-59, is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues, though predominantly in muscle tissue and tumours, and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development, invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.
Concentration: 300 μg/mL
Immunogen: A synthetic peptide of human Lactate Dehydrogenase
Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein
Purification Method: Affinity Purified
Dilution: WB 1:1000-1:2000
Calculated MW: 37kDa
Observed MW: 37kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only