Rev-Erbα/NR1D1 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A20452-20, A20452-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a transcription factor that is a member of the nuclear receptor subfamily 1. The encoded protein is a ligand-sensitive transcription factor that negatively regulates the expression of core clock proteins. In particular this protein represses the circadian clock transcription factor aryl hydrocarbon receptor nuclear translocator-like protein 1 (ARNTL). This protein may also be involved in regulating genes that function in metabolic, inflammatory and cardiovascular processes.
Synonyms: EAR1; hRev; THRA1; THRAL; ear-1; REVERBA; REVERBalpha; Rev-Erbα/NR1D1
GeneID: 9572
Swiss-Prot: P20393
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Calculated Molecular Weight: 67kDa
Observed Molecular Weight: 75kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 280-360 of human Rev-Erbα/NR1D1 (NP_068370.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Nuclear Receptor Signaling, Signal Transduction, Cell Biology Developmental Biology, Growth factors, Endocrine Metabolism, Neuroscience
Recommended Dilutions: WB: 1:500 - 1:1000
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm, Dendrite, dendritic Spine, Nuclear Body, Nucleoplasm, Nucleus
Positive Samples: Hep G2, Mouse liver, Rat brain, Rat lung
Keywords: EAR1, hRev, THRA1, THRAL, ear-1, REVERBA, REVERBalpha, Rev-Erbα/NR1D1
Symbol: NR1D1
Category: Monoclonal Antibodies
Research Use Only