RHOA/RHOB/RHOC Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A4855-20, A4855-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Synonyms: ARH9; ARHC; H9; RHOH9; RHOA/RHOB/RHOC
GeneID: 389/387/388
Swiss-Prot: P08134/P61586/P62745
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 22kDa
Observed Molecular Weight: 22kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-193 of human RHOA/RHOB/RHOC (P08134).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Signal transduction, G protein signaling
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HeLa, MCF7, NIH/3T3, SH-SY5Y, HUVEC, Mouse brain, Mouse kidney, Rat brain
Cellular Location: Cell Cortex, Cell Projection, Cytoplasmic Vesicle, Cytoskeleton, Cytosol, Extra Cellular Exosome, neuron Projection, Nucleus, Plasma Membrane
Category: Monoclonal Antibodies
Citations, Manuals and SDS Available upon request.