RING1B/RNF2 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A24830-20, A24830-100
Citations, Manuals and SDS Available upon request.
Background: Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.
Synonyms: BAP1; DING; BAP-1; HIPI3; RING2; LUSYAM; RING1B; RING1B/RNF2
GeneID: 6045
Swiss-Prot: Q99496
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IHC-P
Calculated Molecular Weight: 38kDa
Observed Molecular Weight: 41kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-336 of human RING1B/RNF2 (NP_009143.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, Epigenetic writers and erasers of core Histones, Chromatin Remodeling
Recommended Dilutions: WB: 1:2000 - 1:6000 | IHC-P: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Chromosome, Nucleus
Positive Samples: Jurkat, 293T, NIH/3T3, Mouse testis
Keywords: 6045, RNF2, BAP-1, BAP1, DING, HIPI3, RING1B, RING2, ring finger protein 2, E3 ubiquitin-protein ligase RING2, HIP2-interacting protein 3, RING finger protein 1B, RING finger protein BAP-1, RING-type E3 ubiquitin transferase RING2, huntingtin-interacting protein 2-interacting protein 3, protein DinG, Q99496, Ring Finger Protein 2, Huntingtin-Interacting Protein 2-Interacting Protein 3, RING-Type E3 Ubiquitin Transferase RING2, HIP2-Interacting Protein 3, RING Finger Protein BAP-1, RING Finger Protein 1B, Protein DinG, E3 Ubiquitin-Protein Ligase RING2, RING Finger Protein 2, EC 2.3.2.27, RING1b, BAP 1, HIP2 interacting protein 3, RING finger protein BAP 1, RING1B/RNF2
Symbol: RNF2
Category: Monoclonal Antibodies
Research Use Only