RIPK1/RIP Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A19580-20, A19580-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth.
Synonyms: RIP; RIP1; AIEFL; IMD57; RIP-1; RIPK1/RIP
GeneID: 8737
Swiss-Prot: Q13546
Reactivity: Human
Tested Applications: ELISA, WB, IP
Calculated Molecular Weight: 76kDa
Observed Molecular Weight: 75kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 289-490 of human RIPK1/RIP (NP_003795.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Cancer, Invasion and Metastasis, Signal Transduction, Kinase, Serine threonine kinases, MAPK-JNK Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Inhibition of Apoptosis, Death Receptor Signaling Pathway, Immunology Inflammation, NF-kB Signaling Pathway, Toll-like Receptor Signaling Pathway
Recommended Dilutions: WB: 1:500 - 1:1000 | IP: 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cell Membrane, Cytoplasm
Positive Samples: Raji, HeLa
Keywords: 8737, Cell death protein RIP, Receptor interacting protein 1, RIP, RIP 1, RIP1, RIPK1, RIP-1, receptor interacting serine/threonine kinase 1, receptor-interacting serine/threonine-protein kinase 1, cell death protein RIP, receptor (TNFRSF)-interacting serine-threonine kinase 1, receptor-interacting protein 1, receptor-interacting protein kinase 1, serine/threonine-protein kinase RIP, Q13546, Receptor Interacting Serine/Threonine Kinase 1, Receptor (TNFRSF)-Interacting Serine-Threonine Kinase 1, Receptor-Interacting Protein Kinase 1, Serine/Threonine-Protein Kinase RIP, Receptor-Interacting Protein 1, Cell Death Protein RIP, Receptor-Interacting Serine/Threonine-Protein Kinase 1, EC 2.7.11.1, TNF, RIPK1/RIP
Symbol: RIPK1
Category: Monoclonal Antibodies
Research Use Only