RKIP Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11537-50, MB11537-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P30086
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P, IP,
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20
Background: Raf kinase inhibitor protein (RKIP) is a member of the phosphatidylethanolamine-binding protein (PEBP) family that associates with Raf-1 and the MEK and MAP kinases. RKIP has been shown to complex with Raf-1, MEK, and ERK. Although MEK and ERK can simultaneously bind RKIP, the association between Raf-1 and RKIP and that of RKIP and MEK are mutually exclusive. Thus, RKIP competitively disrupts the Raf-1-MEK complex and effectively terminates signal transmission from Raf-1 to MAP kinases.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 21 kDa; Observed MW: 21 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of RKIP in rat Brain, C6, 3T3, Hela lysates using RKIP antibody., Immunohistochemistry analysis of paraffin-embedded Human tonsil using RKIP antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.
Alternative Name: PEBP1; PBP; PEBP; Phosphatidylethanolamine-binding protein 1; PEBP-1; HCNPpp; Neuropolypeptide h3; Prostatic-binding protein; Raf kinase inhibitor protein; RKIP
Immunogen: A synthetic peptide of human RKIP
Conjugate: Unconjugated
Modification: Unmodified