RNF14 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A20913-20, A20913-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Synonyms: ARA54; HFB30; TRIAD2; HRIHFB2038; RNF14
GeneID: 9604
Swiss-Prot: Q9UBS8
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Calculated Molecular Weight: 54kDa
Observed Molecular Weight: 54kDa
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human RNF14 (Q9UBS8).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, Nuclear Receptor Signaling, Nuclear hormone receptors, Signal Transduction, Cell Biology Developmental Biology, Ubiquitin
Recommended Dilutions: WB: 1:100 - 1:500
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm, Cytosol, Nucleoplasm, Nucleus
Positive Samples: SH-SY5Y, Jurkat, K-562, Mouse placenta, Rat brain
Keywords: 9604, RNF14, ARA54, HFB30, HRIHFB2038, TRIAD2, ring finger protein 14, E3 ubiquitin-protein ligase RNF14, androgen receptor associated protein 54, Q9UBS8, Ring Finger Protein 14, Androgen Receptor Associated Protein 54, Androgen Receptor-Associated Protein 54, E3 Ubiquitin-Protein Ligase RNF14, RING Finger Protein 14, Triad2 Protein, EC 2.3.2.31
Symbol: RNF14
Category: Monoclonal Antibodies
Research Use Only