RNF7 Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A21137-20, A21137-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and signal transduction. This protein interacts with, and is a substrate of, casein kinase II (CSNK2A1/CKII). The phosphorylation of this protein by CSNK2A1 has been shown to promote the degradation of IkappaBalpha (CHUK/IKK-alpha/IKBKA) and p27Kip1(CDKN1B). Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Synonyms: SAG; ROC2; rbx2; CKBBP1; RNF7
GeneID: 9616
Swiss-Prot: Q9UBF6
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IHC-P
Calculated Molecular Weight: 13kDa
Observed Molecular Weight: 13kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-113 of human RNF7 (NP_055060.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Apoptosis, Cell Cycle, Ubiquitin, Ubiquitin-Proteasome Signaling Pathway, Endocrine Metabolism
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm, Nucleus
Positive Samples: DU145, Mouse heart, Rat brain
Keywords: 9616, sc-5203, sc-5204, sc-292565, CKBBP1, CKII beta binding protein 1, Rbx2, Regulator of cullins 2, RING box protein 2, ring finger protein 7, RNF7, ROC2, SAG, RING-box protein 2, CKII beta-binding protein 1, rbx2, regulator of cullins 2, sensitive to apoptosis gene protein, sensitive to apoptosis, zinc RING finger protein SAG, Q9UBF6, Ring Finger Protein 7, Sensitive To Apoptosis, Zinc RING Finger Protein SAG, Regulator Of Cullins 2, Sensitive To Apoptosis Gene Protein, CKII Beta-Binding Protein 1, RING Finger Protein 7, RING-Box Protein 2, RBX2, sc5203, sc 5203, sc5204, sc 5204, sc292565, sc 292565
Symbol: RNF7
Category: Monoclonal Antibodies
Research Use Only