RPA32/RPA2 mouse mAb
Sizes: 50µl, 100µl
Catalogue Numbers: RA11952-50, RA11952-100
Citations, Manuals and MSDS Available upon request.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Store at: -20°C/1 year
Recommended Dilution: wb dilution 1:2000 icc dilution 1:200
Purification Technology: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
Alternative Names: 60S acidic ribosomal protein P1, AA409079, AI325195, AU020965, HSSB, ik:tdsubc_2g1, M(2)21C, MGC137236, OTTHUMP00000004008, p32, p34, RCJMB04_6d17 replication protein A2, 32kDa, REPA 2, REPA1, REPA2, Replication factor A protein 2, Replication protein A 32 kDa subunit, Replication protein A 32kDa subunit, Replication protein A 34 kDa subunit, Replication protein A, replication protein A1 (70kD), Replication Protein A2 (32kDa), Replication protein A2 32kD, Replication protein A2 32kDa, Replication protein A2, Replication protein A2, 32kDa, RF A, RF-A protein 2, Rf-A2, RFA, RFA2_HUMAN, RP A, RP-A p32, RP-A p34, RP21C, RPA 2, RPA 32, RPA, RPA2, RPA32, RPA34, RPA70, RpLP1, RpP2, xx:tdsubc_2g1, zgc:109822.
Background: function:Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3/RBT1. Interacts with TIPIN.,
Applications: WB, IP, ICC
Species Cross-Reactivity: Human
GeneID (Human): 6118
SWISS: P15927
Source: Mouse
Immunogen: Purified recombinant human RPA32/RPA2 protein fragments expressed in E.coli.
Category: Monoclonal
Research Use Only