RPGR Rabbit mAb
Sizes: 20µl, 100µl
Catalogue Numbers: A23433-20, A23433-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.
Synonyms: CRD; RP3; COD1; PCDX; RP15; XLRP3; orf15; CORDX1; RPGR
GeneID: 6103
Swiss-Prot: Q92834-6
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB, IF/ICC
Calculated Molecular Weight: 52kDa/70kDa/83kDa/90kDa/113kDa/127kDa
Observed Molecular Weight: 113kDa
Immunogen: Recombinant protein of human RPGR.
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Neuroscience
Recommended Dilutions: WB: 1:1000 - 1:3000 | IF/ICC: 1:50 - 1:200
Modifications: Unmodified
Conjugate: Unconjugated
Cellular Location: Cytoplasm, Golgi Apparatus, Centrosome, Cilium Axoneme, Cilium Basal Body, Cytoskeleton, flagellum Axoneme, Microtubule Organizing Center
Positive Samples: Mouse eye, Mouse liver(Low expression control)
Keywords: sc-14672, COD1, CORDX1, CRD, orf15, PCDX, RP15, RP3, RPGR, XLRP3, retinitis pigmentosa GTPase regulator, X-linked retinitis pigmentosa GTPase regulator, retinitis pigmentosa 15, retinitis pigmentosa 3 GTPase regulator, Q92834, 6103, sc14672, sc 14672
Symbol: RPGR
Category: Monoclonal Antibodies
Research Use Only