VDAC1 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB11761-50, MB11761-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P21796
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-P
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100
Background: Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria. In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 31 kDa; Observed MW: 31 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of VDAC1 in rat kidney, mouse kidney lysates using VDAC1 antibody., Western blot analysis of VDAC1 in 293 lysates using VDAC1 antibody., Western blot analysis of VDAC1 in Jurkat, rat Brain, C6 lysates using VDAC1 antibody, Immunohistochemistry analysis of paraffin-embedded Human colon cancer using VDAC1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Alternative Name: VDAC1; PORIN; PORIN-31-HL
Immunogen: A synthetic peptide of human VDAC1
Conjugate: Unconjugated
Modification: Unmodified