VE-Cadherin Rabbit PolymAb®
Sizes: 20μL, 100μL
Catalogue Numbers: A0734PM-20, A0734PM-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a role in endothelial adherens junction assembly and maintenance. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer.
Category: Monoclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 88kDa
Observed Molecular Weight: 90 kDa/120 kDa-140 kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 1003/12562
SWISS: P33151/P55284
Alternate Names: 7B4; CD144
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:4000 IHC-P, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Invasion and Metastasis, Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Cadherins, Tight Junctions, Cytoskeleton, Immunology Inflammation, CDs, Stem Cells, Cardiovascular.
NCBI Alias: CDH5
Research Use Only