Aldose Reductase Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: RA10751-50, RA10751-100
Citations, Manuals and MSDS Available upon request.
Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.
Store at: -20°C/1 year
Recommended Dilution: Western Blot: 1/1000 - 1/2000. Not yet tested in other applications.
Purification Technology: Affinity purification
Alternative Names: AKR1B1, ALDR1, Aldose reductase, AR, Aldehyde reductase, Aldo-keto reductase family 1 member B1
Background: aldo-keto reductase family 1 member B (AKR1B1) Homo sapiens This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This member catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol. Multiple pseudogenes have been identified for this gene. The nomenclature system used by the HUGO Gene Nomenclature Committee to define human aldo-keto reductase family members is known to differ from that used by the Mouse Genome Informatics database. [provided by RefSeq, Feb 2009],
Applications: WB
Species Cross-Reactivity: Human, Mouse, Dog, Rabbit
GeneID (Human): 231
SWISS: P15121
Source: Mouse
Immunogen: Purified recombinant human Aldose Reductase protein fragments expressed in E.coli.
Category: Monoclonal
Research Use Only