K63-linkage Specific Polyubiquitin Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A18164-20, A18164-100
Citations, Manuals and MSDS Available upon request.
Background: Ubiquitination, onetypeofthemostcommonpost-translationalmodification, mediatestheregulationofproteinhomeostasisinvivo.SinceubiquitinitselfcontainsmultiplelysineresiduesandoneN-terminalfreeaminogroup, eighttypesofubiquitinchainscanbeformed.? K63-linked polyubiquitin chains exert nonproteolytic functions in vivo, such as protein trafficking, kinase/phosphatase activation, and DNA damage control, all of which might be important in regulation of cancer survival and development (PMID: 19217402，PMCID: PMC3008764).
Category: Other Modified Antibodies
Applications: DB, ELISA
Cross-reactivity: Human, Mouse, Rat, Other (Wide Range Predicted)
Observed Molecular Weight: 15-200kDa
Immunogen: Synthetic peptide
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: DB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
NCBI Alias: UBB
Research Use Only