Pseudouridine / 5-ribosyluracil Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A18872-20, A18872-100
Citations, Manuals and MSDS Available upon request.
Background: Pseudouridine is the most abundant post-transcriptional RNA modification, which presents mostly in non-coding RNAs such as tRNA, rRNA, snRNA and snoRNA. Pseudouridine impacts various aspects of RNA biology, conferring distinct structural and functional properties to the RNA molecules that it decorates.? It is also reported that pseudouridine has been found in mRNA in both yeast and human by sequencing analysis. Replacing uridine to pseudouridine enhances structural stability of RNA, and is expected to affect rRNA processing, translation and pre-mRNA splicing. Also, aberrant pseudouridylation contributes to a variety of human diseases, including cancer and genetic disorders. Dysregulation of the pseudouridine epitranscriptome can arise from mutations and abnormal expression of pseudouridylation machinery, impacting protein translation and other cellular processes.
Category: Other Modified Antibodies
Applications: DB, ELISA
Cross-reactivity: Species independent
Observed Molecular Weight: Refer to figures
Immunogen: Chemical compounds corresponding to Pseudouridine / 5-ribosyluracil.
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: DB, 1:3000 - 1:10000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
NCBI Alias: Pseudouridine
Research Use Only