Pro-oxidant status evaluation

d-ROMS test:

Evaluates: the free alcohol and hydroperoxyl radicals derived from hydroperoxides present in the sample. The acronym d-ROMs stands for derivates of Reactive Oxygen Metabolites.

Matrix: Serum or Heparinized plasma fresh or frozen

Sector of application: Human and Veterinary

IVD/RUO: For Research Use Only (RUO)

Instrumentation: FREE Systems, manual photometers, multiple analysers, microplate readers

LP-CHOLOX Test:

Used for: the prevention of cardiovascular diseases and, specifically, of atherosclerosis damage.

Evaluates: the level of lipid peroxides in circulation and, in particular, of oxidized cholesterol

Matrix: Serum or plasma, fresh or frozen

Sector of application: Human and Veterinary

IVD/RUO: For Research Use Only (RUO)

Instrumentation: FREE Systems, manual photometers

MAC Test:

Used to: monitor the correct balance between acidity and alkalinity of blood to prevent tissue damage caused by free radicals.

Matrix: fresh whole blood

Instrumentation: FREE Systems, manual photometers

URIN-OX Test:

Used to: evaluate the inflammatory status of the prostate and urinary tract 

Evaluates: the peroxidized compounds in urine

Matrix: fresh urine

Sector of application: Human and Veterinary

IVD/RUO: For Research Use Only (RUO)

Instrumentation: FREE Systems, manual photometers

INDICAN:

Sector of application: Human

IVD/RUO: For Research Use Only (RUO)

Instrumentation: FREE Systems, manual photometers and micro-plate readers

LP SPERM TEST:

Used for: the treatment of masculine infertility and to identify prostatic inflammatory status

Evaluates: the peroxidation status of sperm

Matrix: sperm liquid, nemasperm, fresh spermatic plasma

Sector of application: Human and Veterinary

IVD/RUO: For Research Use Only (RUO)

Instrumentation: FREE Systems, manual photometers

LIPOTISS:

Used to: assess, through tissues, the oxidative state of organisms in which it is not possible to take biological liquids. Main uses in ecological and veterinary research laboratories.

Evaluates: the peroxidation status of tissue 

Matrix: fresh or frozen tissue extracts

Sector of application: Human and Veterinary

IVD/RUO: For Research Use Only (RUO)

Instrumentation: FREE Systems, manual photometers

LIPOCELL:

Used to: evaluate the oxidative state in cell line cultures. Mainly used in research laboratories.

Evaluates: the peroxidation status of cells

Matrix: fresh or frozen cells extracts

Sector of application: Human and Veterinary

IVD/RUO: For Research Use Only (RUO)

Instrumentation: FREE Systems, manual photometers

ROSA TEST:

Used to: measure an inflammatory condition resulting from a bacterial infection of the oral cavity, pharynx or stomach.

Evaluates: the presence of nitric oxide (a radical reactive nitrogen species) in saliva

Matrix: saliva

IVD/RUO: For Research Use Only (RUO)

Qualitative Test: does not require Instrumentation

Antioxidant Status Evaluation

BAP Test:

Used to: evaluate the state of antioxidant defenses and/or the effectiveness of specific antioxidant treatments.

Evaluates: the chemically active antioxidant capacity (scavengers) of the plasma barrier. In particular, this includes antioxidants both of exogenous nature (ascorbic acid and tocopherols) and of endogenous nature (uric acid, bilirubin and albumin).

Matrix: Serum or Heparinized plasma, fresh or frozen

Sector of application: Human and Veterinary

IVD/RUO: For Research Use Only (RUO)

Instrumentation: FREE Systems, manual photometers, multiple analysers, microplate readers

OXY-ADSORBENT TEST:

Used to: evaluate the state of antioxidant defenses and/or the effectiveness of specific antioxidant treatments. Very useful in the veterinary research field.

Evaluates: the total antioxidant barrier understood as the whole of the chemically active capacity (scavengers) and the plasmatic structural component such as mucopolysaccharides, amino acids and proteins (shock adsorbers).

IVD/RUO: For Research Use Only (RUO)

Instrumentation: FREE Systems, manual photometers, microplate readers

-SHP TEST:

Used to: detect conditions lacking thiolic antioxidants and in monitoring the effectiveness of formulations based on active ingredients containing sulfhydryl groups.

Evaluates: the measurement of thiol groups (lipoic acid, glutathione, cysteine) which represent a qualitatively significant component of the plasma antioxidant barrier since they oppose the propagation phase of the radical processes.

Matrix: Serum or plasma fresh

IVD/RUO: For Research Use Only (RUO)

Instrumentation: FREE Systems, manual photometers, microplate readers

ANTI-ROMS TEST:

Used to: evaluate the state of antioxidant defenses and/or the effectiveness of specific antioxidant treatments. It can be used to monitor the effectiveness of food and/or antioxidant formulations.

Evaluates: the plasma antioxidant barrier with two distinct results: rapid exogenous antioxidants such as Vitamin C and Vitamin E and slow endogenous antioxidants such as uric acid, thiol groups and polyphenols.

Matrix: Serum or Heparinized plasma, fresh

Sector of application: Human, Veterinary and Agri-food

IVD/RUO: For Research Use Only (RUO)

Instrumentation: FREE Systems

Control Serum

The Panel Carratelli includes the calibrator and the lyophilized control sera (high and low) useful for calibration on laboratory Instrumentation.

In North America, all tests are classified for research use only (RUO).

While all tests of the Panel Carratelli can be used on standard photometers, some of them can be used on microplate readers or automatic analysers. As an alternative it's possible to run the assays with the dedicated FREE systems (FREE Carpe Diem and FREE DUO). As with all the products developed by Mauro Carratelli, the ease of use combined with the reliability of the system is the focus.

Not sure which test to use? Take a look at our quick guide here.

For more information, or on how to include oxidative stress analysis in your research, please do not hesitate to contact us.