ABflo® 594 Rabbit anti-Human Phospho-PI3KP85α-Y467+P85β-Y464+P55γ-Y199 Monoclonal Antibody
Sizes: 100T, 2 x 100T, 5 x 100T
Catalogue Numbers: AP1489-100, AP1489-200, AP1489-500
Citations, Manuals and MSDS Available upon request.
Background: Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Category: Phosphorylated Antibodies
Application: FC (intra)
Cross Reactivity: Human
Protein Weight: 42-54kDa/81-84kDa Immunogen: Synthetic peptide.
Species: Human
GeneID: 5295/5296/8503
SWISS: P27986/O00459/Q92569
Alternate Names: PIK3R1/PIK3R2/PIK3R3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at 2-8℃. Avoid freeze.|Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilution: FC (intra),5 μl per 10^6 cells in 100 μl volume
Research Areas: Protein phosphorylation
NCBI Alias: PIK3R1/PIK3R2/PIK3R3
Modifications: Phospho Y467/Y464/Y199
Conjugate: ABflo® 594. Ex:588nm. Em:604nm.
Clone Number Info: ARC65199
Research Use Only