Phospho-Bad-S155 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: AP0009-20, AP0009-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL (B-cell lymphoma-extra large) and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform.
Synonyms: BBC2; BCL2L8; Phospho-Bad-S155
GeneID: 572
Swiss Prot: Q92934
Tested Applications: ELISA, WB
Reactivity: Human
Calculated Molecular Weight: 18kDa
Observed Molecular Weight: Refer to figures
Immunogen: A synthetic phosphorylated peptide around S155 of mouse Bad (NP_031548.1?).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Protein phosphorylation, Cancer, Invasion and Metastasis, Signal Transduction, PI3K-Akt Signaling Pathway, ErbB-HER Signaling Pathway, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Inhibition of Apoptosis, Endocrine Metabolism, Insulin Receptor Signaling Pathway, Immunology Inflammation, Neuroscience, Neurodegenerative Diseases
Modifications: Phospho S155
Conjugate: Unconjugated
Cellular Location: Cytoplasm, Mitochondrion Outer Membrane
Keywords: 572, sc-943, BAD, BBC2, BBC6, BCL2L8, BCL2 associated agonist of cell death, bcl2-associated agonist of cell death, BCL-X/BCL-2 binding protein, BCL2-antagonist of cell death protein, BCL2-binding component 6, BCL2-binding protein, bcl-2-binding component 6, bcl-2-like protein 8, bcl-XL/Bcl-2-associated death promoter, bcl2 antagonist of cell death, bcl2-L-8, Q92934, BCL2 Associated Agonist Of Cell Death, Bcl-XL/Bcl-2-Associated Death Promoter, Bcl2 Antagonist Of Cell Death, Bcl-2-Binding Component 6, Bcl-2-Like Protein 8, Bcl2-L-8, BCL2-Antagonist Of Cell Death Protein, Bcl2-Associated Agonist Of Cell Death, BCL-X/BCL-2 Binding Protein, BCL2-Binding Component 6, BCL2-Binding Protein, Bad, Phospho-Bad-S155, PhosphoBad-S155, Phospho Bad-S155, 磷酸化
Symbol: BAD
Category: Phosphorylated Antibodies
Research Use Only