Phospho-BRD4-S484/S488 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: AP1177-20, AP1177-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
Synonyms: CAP; MCAP; HUNK1; HUNKI; FSHRG4; Phospho-BRD4-S484/S488
GeneID: 23476
Swiss Prot: O60885
Tested Applications: ELISA, DB, WB
Reactivity: Human
Calculated Molecular Weight: 152kDa
Observed Molecular Weight: Refer to figures
Immunogen: A synthetic phosphorylated peptide around S484 & S488 of human BRD4 (NP_490597.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: DB: 1:500 - 1:1000 | WB: 1:500 - 1:2000
Research Areas: Epigenetics Nuclear Signaling, Cancer, Tumor suppressors, Signal Transduction, Kinase, Serine threonine kinases
Cellular Location: Chromosome, Nucleus
Keywords: BRD4, CAP, HUNK1, HUNKI, MCAP, bromodomain containing 4, bromodomain-containing protein 4, chromosome-associated protein, O60885, 23476, Bromodomain-containing protein 4, Bromodomaincontaining protein 4, Bromodomain containing protein 4, Protein HUNK1, Phospho-BRD4-S484/S488
Symbol: BRD4
Category: Phosphorylated Antibodies
Research Use Only