Phospho-FOXO3A-S425 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: AP1200-20, AP1200-100
Citations, Manuals and SDS Available upon request.
Background: This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.
Synonyms: FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2; Phospho-FOXO3A-S425
GeneID: 2309
Swiss Prot: O43524
Tested Applications: ELISA, WB, IHC-P
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 71kDa
Observed Molecular Weight: 82kDa
Immunogen: A synthetic phosphorylated peptide around S425 of human FOXO3A (NP_001446.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Protein phosphorylation, Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, MAPK-Erk Signaling Pathway, Cell Biology Developmental Biology, Autophagy, Cell Cycle, Cell Cycle Control-G1 S Checkpoint, Endocrine Metabolism, Insulin Receptor Signaling Pathway, Immunology Inflammation, B Cell Receptor Signaling Pathway
Modifications: Phospho S425
Positive Samples: K-562
Cellular Location: Cytoplasm, Cytosol, Mitochondrial Matrix, Mitochondrial Outer Membrane, Nucleoplasm, Nucleus
Keywords: FOXO2; AF6q21; FKHRL1; FOXO3A; FKHRL1P2; Phospho-FOXO3A-S425
Symbol: FOXO3
Category: Phosphorylated Antibodies
Research Use Only