Phospho-NF-kB p65/RelA-S529 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: AP0944-20, AP0944-100
Citations, Manuals and SDS Available upon request.
Background: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
Synonyms: p65; CMCU; NFKB3; AIF3BL3; Phospho-NF-kB p65/RelA-S529
GeneID: 5970
Swiss Prot: Q04206
Tested Applications: ELISA, WB
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 60kDa
Observed Molecular Weight: 57kDa
Immunogen: A synthetic phosphorylated peptide around S529 of human NF-kB p65/RelA (NP_068810.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Protein phosphorylation, Cancer, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Inhibition of Apoptosis, Death Receptor Signaling Pathway, Endocrine Metabolism, Endocrine and metabolic diseases, Obesity, Immunology Inflammation, B Cell Receptor Signaling Pathway, T Cell Receptor Signaling Pathway, Jak-Stat-IL-6 Receptor Signaling Pathway, NF-kB Signaling Pathway, Toll-like Receptor Signaling Pathway, Neuroscience, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease, Cardiovascular
Modifications: Phospho S529
Positive Samples: HeLa, NIH/3T3
Cellular Location: Cytoplasm, Nucleus
Keywords: 5970, sc-109, sc-7151, sc-372, NFKB 3, NFKB p65, NFKB3, p65, RELA, Transcription factor p65, RELA proto-oncogene, NF-kB subunit, transcription factor p65, NF-kappa-B p65delta3, NF-kappa-B transcription factor p65, nuclear factor NF-kappa-B p65 subunit, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, v-rel avian reticuloendotheliosis viral oncogene homolog A, v-rel reticuloendotheliosis viral oncogene homolog A, Q04206, RELA Proto-Oncogene, NF-KB Subunit, Nuclear Factor Of Kappa Light Polypeptide Gene Enhancer In B-Cells 3, V-Rel Avian Reticuloendotheliosis Viral Oncogene Homolog A, Nuclear Factor NF-Kappa-B P65 Subunit, V-Rel Reticuloendotheliosis Viral Oncogene Homolog A, NF-Kappa-B Transcription Factor P65, Transcription Factor P65, NF-Kappa-B P65delta3, P65, NF-kB p65, CMCU, 磷酸化, 免疫, 炎症, 天然免疫, 感染, 病毒, 自身免疫, NF-kB, TNF, Phospho-NF-kB p65/RelA-S529
Symbol: RELA
Category: Phosphorylated Antibodies
Research Use Only