Phospho-PKM2-S37 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: AP1239-20, AP1239-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.
Synonyms: PK3; TCB; p58; OIP3; PKM2; CTHBP; THBP1; HEL-S-30; Phospho-PKM2-S37
GeneID: 5315
Swiss Prot: P14618
Tested Applications: ELISA, WB
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 58kDa
Observed Molecular Weight: Refer to figures
Immunogen: A synthetic phosphorylated peptide around S37 of human PKM (NP_002645.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Protein phosphorylation, Cancer, Tumor biomarkers, Signal Transduction, Endocrine Metabolism, Carbohydrate metabolism, Warburg Effect
Modifications: Phospho S37
Conjugate: Unconjugated
Cellular Location: Cilium, Cytoplasm, Cytosol, Extra Cellular Exosome, Extra Cellular Region, Extra Cellular Vesicle, Mitochondrion, Nucleus, Rough Endoplasmic Reticulum
Keywords: 5315, sc-65177, sc-65178, sc-65176, sc-135048, sc-292640, CTHBP, OIP 3, OIP3, Opa interacting protein 3, p58, PK2, PK3, PKM, PKM1, PK-M1, PKM1 pyruvate kinase, muscle, Pyruvate kinase 2/3, Pyruvate kinase isozymes M1/M2, Pyruvate kinase muscle isozyme, TCB, THBP1, Tumor M2 PK, PKM2, PKM2 pyruvate kinase, PK-M2, HEL-S-30, pyruvate kinase, pyruvate kinase PKM, OIP-3, OPA-interacting protein 3, PK, muscle type, cytosolic thyroid hormone-binding protein, epididymis secretory protein Li 30, pyruvate kinase 2/3, pyruvate kinase isozymes M1/M2, pyruvate kinase muscle isozyme, thyroid hormone-binding protein 1, thyroid hormone-binding protein, cytosolic, tumor M2-PK, P14618, Pyruvate Kinase M1/2, Cytosolic Thyroid Hormone-Binding Protein, Thyroid Hormone-Binding Protein 1, Pyruvate Kinase Muscle Isozyme, Pyruvate Kinase, Muscle, Pyruvate Kinase 2/3, Tumor M2-PK, P58, Thyroid Hormone-Binding Protein, Cytosolic, Epididymis Secretory Protein Li 30, Pyruvate Kinase Isozymes M1/M2, OPA-Interacting Protein 3, Opa-Interacting Protein 3, Pyruvate Kinase PKM, Muscle Type, EC 2.7.1.40, Phospho-PKM2-S37, PhosphoPKM2-S37, Phospho PKM2-S37, HELS-30, HEL S-30, 磷酸化
Symbol: PKM
Category: Phosphorylated Antibodies
Research Use Only