Phospho-SQSTM1/p62-S349 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A20737-20, A20737-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone.
Synonyms: p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3; Phospho-SQSTM1/p62-S349
GeneID: 8878
Swiss-Prot: Q13501
Reactivity: Human, Mouse, Rat
Tested Applications: ELISA, WB
Calculated Molecular Weight: 48kDa
Observed Molecular Weight: 62kDa
Immunogen: A synthetic phosphorylated peptide around S349 of human SQSTM1/p62 (NP_003891.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Research Areas: Epigenetics Nuclear Signaling, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Autophagy, Endocrine Metabolism, Mitochondrial metabolism, Cardiovascular, Heart
Recommended Dilutions: WB: 1:100 - 1:500
Modifications: Phospho S349
Conjugate: Unconjugated
Cellular Location: Cytoplasm, Cytoplasmic Vesicle, Endoplasmic Reticulum, Late Endosome, Lysosome, Nucleus, P-Body, Autophagosome
Positive Samples: HeLa, C6, NIH/3T3
Keywords: 8878, sc-10117, sc-25575, A170, EBIAP, ORCA, OSIL, p60, P62, SQSTM1, p62B, PDB3, sequestosome 1, Ubiquitin binding protein p62, ZIP3, DMRV, FTDALS3, NADGP, p62, sequestosome-1, EBI3-associated protein of 60 kDa, EBI3-associated protein p60, oxidative stress induced like, phosphotyrosine independent ligand for the Lck SH2 domain p62, phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, ubiquitin-binding protein p62, Q13501, Sequestosome 1, Phosphotyrosine-Independent Ligand For The Lck SH2 Domain Of 62 KDa, EBI3-Associated Protein Of 60 KDa, Ubiquitin-Binding Protein P62, Oxidative Stress Induced Like, P60, Phosphotyrosine Independent Ligand For The Lck SH2 Domain P62, EBI3-Associated Protein P60, Paget Disease Of Bone 3, Sequestosome-1, P62B, SQSTM1 / p62, p62/SQSTM1, sc10117, sc 10117, sc25575, sc 25575, marker, Autophagosomes , Autophagosomes marker, Phospho-SQSTM1/p62-S349
Symbol: SQSTM1
Category: Phosphorylated Antibodies
Research Use Only