Phospho-Tau-Ser416 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: AP1101-20, AP1101-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Synonyms: TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; tau-40; FTDP-17; PPP1R103; Tau-PHF6; Phospho-Tau-Ser416
GeneID: 4137
Swiss Prot: P10636
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 79kDa
Observed Molecular Weight: 95kDa
Immunogen: A synthetic phosphorylated peptide around S416 of human Tau (NP_005901.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Protein phosphorylation, Signal Transduction, Cell Biology Developmental Biology, Apoptosis, Cytoskeleton, Microtubules, Neuroscience, Cell Type Marker, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease, Stem Cells, Neuron marker
Modifications: Phospho Ser416
Positive Samples: NIH/3T3
Cellular Location: Cell Membrane, Cell Projection, Cytoplasm, Cytoplasmic Side, Peripheral Membrane Protein, Axon, Cytoskeleton, Cytosol
Keywords: 4137, sc-1995, sc-1996, sc-5587, DDPAC, FTDP 17, MAPT, MAPTL, MSTD, MTBT1, MTBT2, Neurofibrillary tangle protein, Paired helical filament tau, PHF tau, PPND, TAU, FTDP-17, PPP1R103, microtubule associated protein tau, microtubule-associated protein tau, G protein beta1/gamma2 subunit-interacting factor 1, PHF-tau, neurofibrillary tangle protein, paired helical filament-tau, protein phosphatase 1, regulatory subunit 103, P10636, Microtubule Associated Protein Tau, G Protein Beta1/Gamma2 Subunit-Interacting Factor 1, Protein Phosphatase 1, Regulatory Subunit 103, Neurofibrillary Tangle Protein, Paired Helical Filament-Tau, PHF-Tau, Microtubule-Associated Protein Tau, Isoform 4, Tau, 磷酸化, Phospho-Tau-Ser416
Symbol: MAPT
Category: Phosphorylated Antibodies
Research Use Only