Phospho-TDP-43/TARDBP-S409/S410 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: AP1241-20, AP1241-100
Citations, Manuals and SDS Available upon request.
Background: HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.
Synonyms: ALS10; TDP-43; Phospho-TDP-43/TARDBP-S409/S410
GeneID: 23435
Swiss Prot: Q13148
Tested Applications: ELISA, DB, WB
Reactivity: Human
Calculated Molecular Weight: 45kDa
Observed Molecular Weight: Refer to figures
Immunogen: A synthetic phosphorylated peptide around S409 & S410 of human TDP-43/TARDBP (NP_031401.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.
Recommended Dilutions: DB: 1:500 - 1:1000 | WB: 1:500 - 1:2000
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cell Biology Developmental Biology, Apoptosis, Neuroscience, Neurodegenerative Diseases, Neurodegenerative Diseases Markers, Other Neurological disorders
Modifications: Phospho S409/S410
Conjugate: Unconjugated
Cellular Location: Nucleus
Keywords: 23435, sc-102127, sc-292299, ALS10, phospho(409/410)-TDP43, TAR DNA binding protein, TAR DNA binding protein 43, TARDBP, TDP 43, TDP43, phospho TDP43, TDP-43, TAR DNA-binding protein 43, TAR DNA-binding protein-43, Q13148, TAR DNA Binding Protein, TAR DNA-Binding Protein 43, TAR DNA-Binding Protein-43, Phospho-TDP-43/TARDB-S409/S410
Symbol: TARDBP
Category: Phosphorylated Antibodies
Research Use Only