Phospho-Tyk2-Y1054/1055 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: AP0543-20, AP0543-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35.
Synonyms: JTK1; IMD35; Phospho-Tyk2-Y1054/1055
GeneID: 7297
Swiss-Prot: P29597
Reactivity: Mouse, Rat
Calculated Molecular Weight: 134kDa
Observed Molecular Weight: 134kDa
Immunogen: A synthetic phosphorylated peptide around Y1054 & Y1055 of human Tyk2 (NP_003322.3).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Tested Applications: ELISA, WB
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles. | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000
Research Areas: Protein phosphorylation, Signal Transduction, Kinase, Tyrosine kinases, ErbB-HER Signaling Pathway, Immunology Inflammation
Modifications: Phospho Y1054/1055
Conjugate: Unconjugated
Positive Samples: NIH/3T3
Cellular Location: Cytoplasm, Cytoskeleton, Cytosol, Extra Cellular Exosome, Nucleus,
Category: Phosphorylated Antibodies
Citations, Manuals and SDS Available upon request.