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AP3B2 Rabbit pAb - A13808

AP3B2 Rabbit pAb - A13808

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$128.00 USD
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AP3B2 Rabbit pAb

Sizes: 20µl, 100µl

Catalogue Numbers: A13808-20, A13808-100

Citations, Manuals and SDS Available upon request.

Background: Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy.

Synonyms: DEE48; NAPTB; EIEE48; AP3B2

GeneID: 8120

Swiss Prot: Q13367

Tested Applications: ELISA, WB

Reactivity: Human, Mouse, Rat

Calculated Molecular Weight: 119kDa

Observed Molecular Weight: 130kDa

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 833-1082 of human AP3B2 (NP_004635.2).

Immunogen Species: Human

Host: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.

Recommended Dilutions: WB: 1:500 - 1:2000

Research Areas: ATM Signaling Pathway, Neuroscience

Modifications: Unmodified

Conjugate: Unconjugated

Positive Samples: Jurkat, Mouse brain, Rat brain

Cellular Location: Cytoplasmic Side, Cytoplasmic Vesicle, Golgi Apparatus, Peripheral Membrane Protein, clathrin-coated Vesicle Membrane,

Keywords: 8120, AP 3 complex subunit beta 2, AP3B2, Beta 3B adaptin, NAPTB, EIEE48, adaptor related protein complex 3 beta 2 subunit, AP-3 complex subunit beta-2, Neuronal adaptin-like protein, beta-subunit, adaptor protein complex AP-3 subunit beta-2, adaptor-related protein complex 3 subunit beta-2, beta-3B-adaptin, clathrin assembly protein complex 3 beta-2 large chain, neuron-specific vesicle coat protein beta-NAP, Q13367, Adaptor Related Protein Complex 3 Subunit Beta 2, Adaptor Related Protein Complex 3 Beta 2 Subunit, Clathrin Assembly Protein Complex 3 Beta-2 Large Chain, Neuron-Specific Vesicle Coat Protein Beta-NAP, Adaptor Protein Complex AP-3 Subunit Beta-2, Beta-3B-Adaptin, Adaptor-Related Protein Complex 3 Subunit Beta-2, Neuronal Adaptin-Like Protein, Beta-Subunit, AP-3 Complex Subunit Beta-2, DKFZp686D17136

Symbol: AP3B2

Category: Polyclonal Antibodies

Research Use Only