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Microfluidic and Microfabricated Devices

OMEGA SERIES

NEURONAL CO-CULTURE DEVICES

Neuronal microfluidic co-culture and compartmentalization devices OMEGA-4 and OMEGA-96 by eNUVIO for 2 and 48 experiments, respectively.

The OMEGA double-chamber microfluidic devices are perfectly suited for experiments involving neuronal co-culture and compartmentalization.

The unique design requires only two chambers per experiment, effectively doubling the number of experiments per area compared to conventional co-culture devices.

Each set of two culture chambers are physically separated by a series of microfluidic channels. The small size of the microchannels serve to fluidically isolate each of the adjoined chambers, but are large enough to allow neurites/axons to project into and interact with cultures located in the adjacent chamber.

OMEGA devices feature identical culture chambers on either side of the microchannels and are available in 4-well and 96-well format.
The OMEGA4-2mini features smaller chambers on one side of the microchannel so you can save on cells and culture media. The OMEGA4-2mini is available in 4-well format.

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OMEGAACE

TRIPLE-CHAMBER NEURONAL CO-CULTURE DEVICES

Triple neuronal microfluidic co-culture and compartmentalization devices OMEGA-ACE, OMEGA-ACE-2mm and OMEGA-96-ACE by eNUVIO for 1 and 32 experiments, respectively.

The OMEGAACE devices each contain three serially-adjoined culture chambers, providing researchers with the ability to perform more specialized experiments.

OMEGAACE devices can be used for in vitro triple co-culture studies of neurodegeneration, neuromuscular junction (NMJ), nigrostriatal pathway, pain, myelination, or chemotactic factors. They also suit themselves for studying neuronal propagation of toxic or misfolded proteins! In single culture applications, the OMEGAACE can serve as a compartmentalization tool to separate the somatic, proximal axonal and distal axonal (growth cone) components of neurons.

Available in three different formats with differently sized middle chambers.


OMEGAAG

AXON GUIDANCE AND CHEMOTAXIS DEVICE

Photograph of eNUVIO's OMEGA AG device with three chambers. Source chamber 1 is filled with blue liquid, source chamber two is filled with red liquid, neuronal chamber is filled with colorless liquid, waste chamber is filled with silver liquid.

The OMEGAAG device is designed to help researchers study axon guidance and chemotactic factors in vitro.

The device has 4 chambers that are each connected to a central viewing area via a series of microchannels. The flow of fluid across the microchannels can be controlled by simply adjusting the relative fluid volumes in each of the chambers. This asymmetric volume loading of the chambers can serve to fluidically isolate adjacent chambers (like for our original OMEGA device), but can also be used to control the direction of flow into and out from the viewing area.


MICROFLUIDIC + 3D CULTURE DEVICES


OMEGANMJ

NEUROMUSCULAR JUNCTION DEVICES

Neuron-3d skeletal muscle microfluidic co-culture device OMEGA-NMJ refill kit by eNUVIO. Each experimental units consists of one neuronal chamber (filled with red colorant) and one 3D skeletal muscle chamber with micropillars (filled with blue colorant) connected by microfluidic microchannels. This PDMS based device is pre-bonded to a PDMD base.

The OMEGANMJ is specifically designed to best recapitulate neuromuscular synaptic physiology in vitro.

Motor neurons seeded in the neuronal culture chamber extend axons into the adjoined oval muscle chamber through a series of microchannels that serve to fluidically isolate the two culture chambers. This way, the somatic motor neuron components are not directly exposed to the muscle they innervate, forming a system that more closely resembles the native neuromuscular physiology.

Available in 4-well and and soon in 96-well format.


3D CULTURE


OMEGAMP

3D SKELETAL MUSCLE CULTURE DEVICES

3D skeletal muscle culture devices OMEGA-MP and OMEGA-96-MP by eNUVIO for 2 and 96 experiments, respectively.

Looking to advance your skeletal muscle research projects using 3D cultures? Now you can easily access this exciting new culture technology using the OMEGAMP devices.

Compared to monolayer muscle cultures that are known to detach from the surface after a short period of time, 3D skeletal muscle is stable for longer-term culture applications and matures more rapidly and completely. This increased physiological relevance of this system makes it ideal for the development of new disease models of both muscle and neuromuscular disorders.

Available in 2-well and 96-well format.

12 products
  • Evaporation Minimizers - for Use with All Round OMEGA Series Devices - Pack of 4
    $50.40 USD
    $50.40 USD
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  • Microscopy adapter - Slide-size microscopy adapter
    $50.40 USD
    $50.40 USD
    Sold out
  • OMEGA-MP - 3D Muscle Microtissue Device
    $432.00 USD
    $432.00 USD
    Sold out
  • OMEGA-NMJ - Neuromuscular Junction Device
    $477.00 USD
    $477.00 USD
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  • OMEGA-AG - Axon Guidance and Chemotaxis Neuronal Microfluidic Device
    $477.00 USD
    $477.00 USD
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  • OMEGA-ACE-96 - HTS Microplate Format; Triple-Chamber Compartmentalization and Co-Culture Device
    $891.00 USD
    $891.00 USD
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  • OMEGA-ACE-2mm - Triple-Chamber Neuronal Compartmentalization and Co-Culture Device
    $337.50 USD
    $337.50 USD
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  • OMEGA-ACE- Triple-Chamber Neuronal Compartmentalization and Co-Culture Device
    $337.50 USD
    $337.50 USD
    Sold out