ATP1A2 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A13805-20, A13805-100
Citations, Manuals and SDS Available upon request.
Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood.
Synonyms: FHM2; MHP2; DEE98; FARIMPD; ATP1A2
GeneID: 477
Swiss Prot: P50993
Tested Applications: ELISA, WB
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 112kDa
Observed Molecular Weight: 112kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human ATP1A2 (NP_000693.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:100 - 1:500
Research Areas: Cancer, Signal Transduction, Endocrine Metabolism
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: Mouse skeletal muscle
Cellular Location: Cell Membrane, Membrane, Multi-pass Membrane Protein,
Keywords: 477, sc-31391, alpha 2 ATPase, ATP1A2, FHM2, KIAA0778, MHP2, Sodium pump subunit alpha 2, ATPase Na+/K+ transporting subunit alpha 2, sodium/potassium-transporting ATPase subunit alpha-2, ATPase Na+/K+ transporting alpha 2 polypeptide, Na(+)/K(+) ATPase alpha-2 subunit, Na+/K+ ATPase, alpha-A(+) catalytic polypeptide, alpha-B polypeptide, sodium pump subunit alpha-2, sodium-potassium ATPase catalytic subunit alpha-2, sodium/potassium-transporting ATPase alpha-2 chain, P50993, ATPase Na+/K+ Transporting Subunit Alpha 2, Sodium Pump Subunit Alpha-2, Sodium/Potassium-Transporting ATPase Subunit Alpha-2, Sodium-Potassium ATPase Catalytic Subunit Alpha-2, Na(+)/K(+) ATPase Alpha-2 Subunit, ATPase, Na+/K+ Transporting, Alpha 2 (+) Polypeptide, Sodium/Potassium-Transporting ATPase Alpha-2 Chain, Alpha 2 Polypeptide, Alpha-A(+) Catalytic Polypeptide, ATPase Na+/K+ Transporting Alpha 2 Polypeptide, Alpha-B Polypeptide, Migraine, Hemiplegic 2, EC 3.6.3.9, alpha 2 ATPase
Symbol: ATP1A2
Category: Polyclonal Antibodies
Research Use Only