LysRS/KARS Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A13772-20, A13772-100
Citations, Manuals and SDS Available upon request.
Background: Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Lysyl-tRNA synthetase is a homodimer localized to the cytoplasm which belongs to the class II family of tRNA synthetases. It has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: KRS; KARS; KARS2; LEPID; CMTRIB; DEAPLE; DFNB89; LysRS/KARS
GeneID: 3735
Swiss Prot: Q15046
Tested Applications: ELISA, WB, IF/ICC
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 68kDa
Observed Molecular Weight: 75kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 298-597 of human LysRS/LysRS/KARS (NP_005539.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000 | IF/ICC: 1:50 - 1:200
Research Areas: Epigenetics Nuclear Signaling
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: HepG2, Jurkat, HeLa, 293T, Mouse heart, Mouse kidney, Rat liver
Cellular Location: Cell Membrane, Cytoplasm, Mitochondrion, Nucleus, Peripheral Membrane Protein, Secreted,
Keywords: 3735, KARS, CMTRIB, DFNB89, KARS1, KARS2, KRS, lysyl-tRNA synthetase, lysine--tRNA ligase, lysRS, lysine tRNA ligase, Q15046, Lysyl-TRNA Synthetase, Lysine TRNA Ligase, LysRS, Deafness, Autosomal Recessive 89, Lysine--TRNA Ligase, EC 2.7.7.-, EC 6.1.1.6, KIAA0070, Lysine tRNA ligase, lysyl tRNA synthetase, LysRS/KARS
Symbol: KARS1
Category: Polyclonal Antibodies
Research Use Only