PHF6 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A18149-20, A18149-100
Citations, Manuals and SDS Available upon request.
Background: This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by cognitive disability, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms.
Synonyms: BFLS; BORJ; CENP-31; PHF6
GeneID: 84295
Swiss Prot: Q8IWS0
Tested Applications: ELISA, WB
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 41kDa
Observed Molecular Weight: 41kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-112 of human PHF6 (NP_115834.1).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Epigenetics Nuclear Signaling, RNA Binding
Positive Samples: Rat thymus
Cellular Location: Chromosome, Nucleus, centromere, Kinetochore, Nucleolus
Keywords: 84295, sc-131747, PHF6, BFLS, BORJ, CENP-31, PHD finger protein 6, PHD-like zinc finger protein, centromere protein 31, Q8IWS0, Phf6, PHD Finger Protein 6, PHD-Like Zinc Finger Protein, Centromere Protein 31, Borjeson-Forssman-Lehmann Syndrome, KIAA1823
Symbol: PHF6
Category: Polyclonal Antibodies
Research Use Only