UBR5 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A13816-20, A13816-100
Citations, Manuals and SDS Available upon request.
Background: This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation.
Synonyms: DD5; EDD; HYD; EDD1; UBR5
GeneID: 51366
Swiss Prot: O95071
Tested Applications: ELISA, WB
Reactivity: Human
Calculated Molecular Weight: 309kDa
Observed Molecular Weight: 300kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 550-760 of human UBR5 (NP_056986.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:2000
Research Areas: Epigenetics Nuclear Signaling, Cell Biology Developmental Biology, Cell Cycle, Ubiquitin, Ubiquitin-Proteasome Signaling Pathway
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: U-87MG, 293T, Jurkat, HeLa
Cellular Location: Nucleus
Keywords: 51366, UBR5, DD5, EDD, EDD1, HYD, ubiquitin protein ligase E3 component n-recognin 5, E3 ubiquitin-protein ligase UBR5, E3 identified by differential display, E3 ubiquitin-protein ligase, HECT domain-containing 1, HECT-type E3 ubiquitin transferase UBR5, hyperplastic discs protein homolog, progestin-induced protein, O95071, Ubiquitin Protein Ligase E3 Component N-Recognin 5, E3 Ubiquitin-Protein Ligase, HECT Domain-Containing 1, HECT-Type E3 Ubiquitin Transferase UBR5, Hyperplastic Discs Protein Homolog, Progestin-Induced Protein, E3 Ubiquitin Protein Ligase, HECT Domain Containing, 1, E3 Identified By Differential Display, E3 Ubiquitin-Protein Ligase UBR5, EC 2.3.2.26, KIAA0896, HHYD
Symbol: UBR5
Category: Polyclonal Antibodies
Research Use Only