A2ML1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-91925-60, E-AB-91925-120, E-AB-91925-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: A2ML1
Target Synonym: CPAMD9; p170; A2ML1
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: A8K2U0
Background: This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein is thought to be an N-glycosylated monomeric protein that acts as an inhibitor of several proteases. It has been shown to form covalent interactions with proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID:20805888). Mutations in these gene have also been associated with some cases of Noonan syndrome (NS; PMID:24939586) as well as some cases of otitis media (PMID:26121085). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]
Concentration: 1mg/mL
Immunogen: A synthetic peptide of human A2ML1
Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Observed MW: 161kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only