AARS Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-16145-60, E-AB-16145-120, E-AB-16145-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: AARS
Target Synonym: AARS; AI316495; Alanine tRNA ligase 1; cytoplasmic; Alanine tRNA ligase; Alanine tRNA ligase cytoplasmic; Alanine--tRNA ligase; Alanyl tRNA synthetase; Alanyl tRNA synthetase cytoplasmic; Alanyl-tRNA synthetase; AlaRS; C76919; CMT2N; cytoplasmic; EC 6.1.1.7; MGC37368; Renal carcinoma antigen NY REN 42; Renal carcinoma antigen NY-REN-42; SYAC
Research Areas: Epigenetics and Nuclear Signaling
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P49588
Background: The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure.
Concentration: 0.6 mg/mL
Immunogen: Synthetic peptide of human AARS
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only