ABCA1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-66766-60, E-AB-66766-120, E-AB-66766-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: ABCA1
Target Synonym: ABCA1; ABC-1; ABC1; CERP; HDLDT1; TGD
Research Areas: Cancer,Cardiovascular,Metabolism,Neuroscience,Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Mouse
Application: IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: O95477
Background: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.
Concentration: 1 mg/mL
Immunogen: Recombinant fusion protein of human ABCA1
Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IF 1:50-1:200
Calculated MW: 254kDa
Observed MW: 270KDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only