ACPT Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS65947-50, BS65947-100
Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Swiss-Prot: Q9BZG2
Host: Rabbit
Reactivity: Human, Mouse, Rat, Dog,Horse,
Applications: FCM
All Applications: Flow-Cyt=0.2ug/test
Background: Acid phosphatases are enzymes capable of hydrolyzing orthophosphoric acid esters in an acid medium. This gene is upregulated by androgens and is down-regulated by estrogens in the prostate cancer cell line. ACPT dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic cleavage. ACPT is predominantly expressed in testis but exhibits a lower level of expression in testicular cancer tissues than in normal tissues. ACPT has structural similarity to prostatic and lysosomal acid phosphatases. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Purification and Purity: affinity purified by Protein A
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ACPT Polyclonal Antibody detects endogenous levels of ACPT protein.
Bioworld Molecular Weight: 47kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: Acid phosphatase testicular; Testicular acid phosphatase; PPAT_HUMAN.
Immunogen: KLH conjugated synthetic peptide derived from human ACPT:65-160/437
Conjugate: Unconjugated
Modification: Unmodified