Active CASP3 Monoclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-22115-60, E-AB-22115-120, E-AB-22115-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: Active Caspase-3
Target Synonym: A830040C14Rik; Apopain; CASP-3; CASP3; CASP3; Casp3a; Caspase 3; Caspase 3; apoptosis-related cysteine peptidase; Caspase 3; apoptosis-related cysteine protease; Caspase 3; apoptosis-related cysteine protease a; Caspase-3 subunit p12; CC3; CPP-32; CPP32; CPP32B; Cysteine protease CPP32; EC 3.4.22.56; LICE; mldy; OTTHUMP00000165052; OTTHUMP00000165053; OTTHUMP00000165054; PARP cleavage protease; Procaspase3; Protein Yama; SCA 1; SCA-1; SREBP cleavage activity 1; Yama
Research Areas: Cancer, Cell Biology, Metabolism, Neuroscience
Conjugation: Unconjugated
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC-p, IF
Isotype: IgG
Clonality: Monoclonal
Clone No.: Clone:5A2
UNIProt ID: P42574
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.
Concentration: 1 mg/mL
Immunogen: Recombinant Protein
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method: Protein A purification
Dilution: WB 1:500-1:1000, IHC 1:100-1:200, IF 1:100-1:200
Observed MW: 17kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only