ADCY5/6 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BZ16420-50, BZ16420-100
Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Swiss-Prot: O95622/O43306
Host: Rabbit
Reactivity: Human, Mouse, Rat
Applications: WB, IHC-F, IHC-P, ICC/IF, ELISA
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000
Background: ADCY5 encodes a member (adenylate cyclase 5) of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for ADCY5.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 139 kDa; Observed MW: 139 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of ADCY5/6 in various lysates using ADCY5/6 antibody., Western blot analysis of ADCY5/6 in COLO205 lysates using A Cyclase V/VI antibody., Western blot analysis of ADCY5/6 in COLO25 lysates using ADCY5/6 antibody. The Lane on the right is blocked with the synthesized peptide., Western blot analysis of ADCY5/6 in HUVEC lysates using ADCY5/6 antibody.
Alternative Name: ADCY5; Adenylate cyclase type 5; ATP pyrophosphate-lyase 5; Adenylate cyclase type V; Adenylyl cyclase 5; ADCY6; KIAA0422; Adenylate cyclase type 6; ATP pyrophosphate-lyase 6; Adenylate cyclase type VI; Adenylyl cyclase 6; Ca(2+)-inhibitabl
Immunogen: The antiserum was produced against synthesized peptide derived from human ADCY5/6. AA range:931-980
Conjugate: Unconjugated
Modification: Unmodified