ADH5 Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS6512-50, BS6512-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P11766
Host: Rabbit
Reactivity: Human, Mouse
Applications: WB
All Applications: WB 1:500 - 1:2000
Background: ADH5 (alcohol dehydrogenase 5 (class III)), also known as FDH (formaldehyde dehydrogenase), ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ADH5 polyclonal antibody detects endogenous levels of ADH5 protein.
Bioworld Molecular Weight: ~ 40 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western Blot analysis of ADH5 polyclonal antibody
Alternative Name: Alcohol dehydrogenase class-3; Alcohol dehydrogenase 5; Alcohol dehydrogenase class chi chain; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; ADH5; ADHX; FDH
Immunogen: Recombinant full length Human ADH5.
Conjugate: Unconjugated
Modification: Unmodified