Adiponectin Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10499-50, MB10499-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: Q60994
Host: Rabbit
Reactivity: Mouse, Rat
Applications: WB, IHC-F, IHC-P, ICC/IF
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Background: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG
Bioworld Molecular Weight: Calculated MW: 27 kDa; Observed MW: 30 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Adiponectin in rat fat lysates using Adiponectin antibody., Western blot analysis of Adiponectin in 3T3-L1 lysates using Adiponectin antibody.
Alternative Name: Ad; APN; Acdc; Adid; apM1; 30kDa; GBP28; adipo; Acrp30
Immunogen: Recombinant protein of mouse Adiponectin
Conjugate: Unconjugated
Modification: Unmodified