ADRA1D Polyclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: BS61380-50, BS61380-100
Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Swiss-Prot: P25100
Host: Rabbit
Reactivity: Human
Applications: WB,
All Applications: WB: 1:500~1:1000
IHC: 1:50~1:200
Background: α1D-adrenergicreceptors(α1D-ARs)couple to Gq/11 and participate directly in sympatheticregulation ofsystemic blood pressure byvasoconstriction. α1D-AR can form hetero-oligomers with α1B receptors. α1D-AR transcripts are abundant in prostate and aorta. α1A adrenergicreceptors(α1A-ARs) mediate actionsin the sympathetic nervoussystem through the binding of the catecholamines, epinephrine and norepinephrine. α1A-adrenergic receptors couple to Gq/11 and regulate blood pressure due to changesin vascular tone and cardiac output. Alternative splicing of this gene generatesfour isoforms with distinct C-termini, and the different expression profile of these subtypes produces distinct patterns of activation. α1A-AR transcripts are abundant in heart, brain, liver, and prostate. α1A-AR transcriptsizes of 6.0, 4.0, 3.0, and 2.0 kb have been detected in liver. α1A-AR transcriptsizes of 6.0, 4.0 and 3.0 kb transcripts have been detected in heart, and 6.0 kb and 4.0 kb transcripts have been detected in prostate.
Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: ADRA1D polyclonal antibody detects endogenous levels of ADRA1D protein.
Bioworld Molecular Weight: ~ 60 kDa
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot (WB) analysis of ADRA1D polyclonal antibody at 1:500 dillution
Lane 1: MCF-7 whole cell lysate (40μg)
Alternative Name: Alpha-1D adrenergic receptor; Alpha-1A adrenergic receptor; Alpha-1D adrenoreceptor; Alpha-1D adrenoceptor; Alpha-adrenergic receptor 1a; ADRA1D; ADRA1A
Immunogen: Synthetic peptide, corresponding to amino acids456-501 of Human ADRA1D
Conjugate: Unconjugated
Modification: Unmodified