AF10 Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10506-50, MB10506-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P55197
Host: Rabbit
Reactivity: Human
Applications: WB,IHC-P
All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100
Background: Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302).
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of AF10 in Hela, K562Lysates using AF10 antibody.
Bioworld Molecular Weight: Calculated MW: 113 kDa; Observed MW: 140 kDa
Specificity: IgG
Alternative Name: MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein
Immunogen: Recombinant protein of human AF10
Conjugate: Unconjugated
Modification: Unmodified