AFP Monoclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-22033-60, E-AB-22033-120, E-AB-22033-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: AFP alpha 1 Fetoprotein
Target Synonym: Afp; AFPD; Alpha fetoglobulin; Alpha fetoprotein; Alpha fetoprotein precursor; Alpha-1-fetoprotein; Alpha-fetoglobulin; Alpha-fetoprotein; alpha-fetoprotein; Hereditary persistence of; included; FETA; FETA; Hereditary persistence of alpha fetoprotein; HPAFP
Research Areas: Cancer, Cardiovascular, Developmental Biology
Conjugation: Unconjugated
Host: Mouse
Species Reactivity: Human
Application: WB, IHC-p, IF
Isotype: IgG
Clonality: Monoclonal
Clone No.: Clone:2L6
UNIProt ID: P02771
Background: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Concentration: 1 mg/mL
Immunogen: Synthetic Peptide
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method: Protein A purification
Dilution: WB 1:500-1:3000, IHC 1:50-1:300, IF 1:100-1:300
Observed MW: 70kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only