AFP Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-40293-60, E-AB-40293-120, E-AB-40293-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: AFP
Target Synonym: Afp; AFPD; Alpha fetoglobulin; Alpha fetoprotein precursor; Alpha-1-fetoprotein; FETA; Hereditary persistence of alpha fetoprotein; HPAFP
Research Areas: Cancer, Cardiovascular, Developmental Biology
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P02772
Background: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Concentration: 1.1mg/mL
Immunogen: Recombinant Mouse Afp protein expressed by E.coli
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification Method: Antigen Affinity Purification
Dilution: WB:1:500-1:1000, IHC 1:200-1:500, IF 1:100-1:200
Calculated MW: 67 kDa
Observed MW: 73 kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only