AK2 Polyclonal Antibody
Sizes: 120μL, 200μL
Catalogue Numbers: E-AB-92548-120, E-AB-92548-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: AK2
Target Synonym: AK2; ADK2
Research Areas: Cancer, Cell Biology, Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: WB
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P54819
Background: Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human AK2
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000
Calculated MW: 14kDa/21kDa/22kDa/24kDa/25kDa/26kDa
Observed MW: 26kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only