AKT (2A1) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB3288-50, MB3288-100
Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Swiss-Prot: P31749
Host: Mouse
Reactivity: Human, Rat, Mouse
Applications: IHC-P
All Applications: IHC: 1/50-1/100
Background: Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: IgG1
Bioworld Molecular Weight: -
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Immunohistochemistry analysis of paraffin-embedded Human Lung Carcinoma Tissue using AKT antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval., Immunohistochemical analysis of paraffin-embedded Human tonsils using AKT antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.
Alternative Name: AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha
Immunogen: Synthetic peptide conjugated to KLH.
Conjugate: Unconjugated
Modification: Unmodified