ALAD Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-68421-60, E-AB-68421-120, E-AB-68421-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: ALAD
Target Synonym: ALAD; ALADH; PBGS
Research Areas: Cell Biology, Cardiovascular
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: WB, IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P13716
Background: The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Concentration: 1 mg/mL
Immunogen: Recombinant fusion protein of human ALAD
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IF 1:50-1:200
Calculated MW: 36kDa/39kDa
Observed MW: 35kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only