ALB Monoclonal Antibody
Catalogue Numbers: MB66781-50, MB66781-100
Sizes: 50µl, 100µl
Product: Mouse IgG2a. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Swiss-Prot: P02768
Host: Mouse
Reactivity: Human
Applications: WB
All Applications: WB (1/500 - 1/1000)
Background: Serum albumin (ALB), the main protein in plasma, has a very good binding capacity for water, fatty acids, calcium, sodium, bilirubin, hormones, potassium and drugs. The primary function of ALB is to regulate the colloidal osmotic pressure of blood. Albumin is synthesized in the liver as preproalbumin, which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted form of albumin. Mutations in the ALB gene may result in familial dysalbuminemic hyperthyroxinemia (FDH), a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T4. FDH is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian populations.
Purification and Purity: This antibody is purified through a protein G column.
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: Recognizes endogenous levels of ALB protein.
Extra Notes: Western blot analysis of ALB expression in T47D (A) whole cell lysates.
Bioworld Molecular Weight: ~ 64 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Name: Serum albumin
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human ALB. The exact sequence is proprietary.
Conjugate: Unconjugated
Modification: Unmodified